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Research Services

microRNA Sequencing

Applications

  • Identification of miRNA biomarkers for diagnosis and prognosis of diseases.

  • Characterization of miRNA-based therapeutic targets.

  • Investigating the mechanisms drug respins or resistance.

  • Study of miRNA-mediated gene regulation in different biological systems.

Decoding Post-Transcriptional Regulation with miRNA-Seq

microRNAs (miRNAs) are small, non-coding RNA molecules that play important roles in regulating gene expression at the post-transcriptional level. miRNA sequencing allows researchers to measure the abundance of miRNAs in a sample and to compare the miRNA expression levels between different samples.

Image by Lucas Vasques
What's Included
  • Sample Receipt and Initial QC

  • Library Construction and QC

  • Sequencing and Data Delivery

  • Bioinformatics Analysis

Input Requirements
  • ≥ 2 μg of total RNA or ≥ 10 ng of exosomal RNA

  • A260/280 = 1.8-2.0

  • A260/230 ≥ 1.8

Data Deliverable
  • Summary of length distribution

  • Identification & characterization of miRNAs

  • Classification & annotation of miRNAs

  • Quantification & differential expression analysis

  • Functional enrichment analysis

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Serum Exosomal MicroRNA, miR-10b-5p, as a Potential Diagnostic Biomarker for Early-Stage Hepatocellular Carcinoma. J Clin Med 2020, 9(1).

Collaborate with us

We act as scientific partners to help integrate human genetics into drug discovery and development. Whether identifying new targets, evaluating clinical-stage assets, or refining development strategies, Genomics delivers customised, data-driven approaches tailored to your strategic goals. Together we can accelerate drug discovery and advance population health to help people live longer, healthier lives.

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