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Abstract illustration of a DNA helix in blue over a dark background.

Research Services

microRNA Sequencing

Applications

  • Identification of miRNA biomarkers for diagnosis and prognosis of diseases.

  • Characterization of miRNA-based therapeutic targets.

  • Investigating the mechanisms drug respins or resistance.

  • Study of miRNA-mediated gene regulation in different biological systems.

Decoding Post-Transcriptional Regulation with miRNA-Seq

microRNAs (miRNAs) are small, non-coding RNA molecules that play important roles in regulating gene expression at the post-transcriptional level. miRNA sequencing allows researchers to measure the abundance of miRNAs in a sample and to compare the miRNA expression levels between different samples.

AGTC Genomics

What's Included

  • Sample Receipt and Initial QC

  • Library Construction and QC

  • Sequencing and Data Delivery

  • Bioinformatics Analysis

Input Requirements

  • ≥ 2 μg of total RNA or ≥ 10 ng of exosomal RNA

  • A260/280 = 1.8-2.0

  • A260/230 ≥ 1.8

Data Deliverable

  • Summary of length distribution

  • Identification & characterization of miRNAs

  • Classification & annotation of miRNAs

  • Quantification & differential expression analysis

  • Functional enrichment analysis

Image shows HepG2 results, Exo-miRNA seq, and network analysis using IPA.

Serum Exosomal MicroRNA, miR-10b-5p, as a Potential Diagnostic Biomarker for Early-Stage Hepatocellular Carcinoma. J Clin Med 2020, 9(1).

Collaborate with us

AGTC Genomics collaborates with researchers to apply genomics, multi-omics, and data-driven insights across discovery, translation, and development—accelerating innovation and real-world health impact.

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