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DNA double helix illustration on a dark purple background, genetic science concept.

Research Services

De novo Sequencing

Applications

  • Virulence research

  • Drug resistance mechanism

  • Vaccine development

  • Epidemiology

  • Microbial evolution

From Microbes to Plants:
The Power of De Novo Sequencing

De novo sequencing can sequence the genome of a species without any reference genome information, splice and assemble it by bioinformatics analysis methods, and obtain the genome sequence map of the species, to promote the follow-up research of the species. It offers reference genome assembly for rarely studied species. Using de novo sequencing, researchers can obtain the genomic information of microbes providing a fresh start for exploring the genetic structure and functions, studying the evolutionary origin of microbial populations, as well as developing potential applications of these abundant microbes in medicine, disease, agriculture, and the environment. De novo sequencing can also be applied to research of animals, and plants, including phylogenetic studies, analysis of species diversity, genetic markers, and other genomic research.

Image by National Institute of Allergy and Infectious Diseases

What's Included

  • Sample Receipt and Initial QC

  • Library Construction and QC

  • Sequencing and Data Delivery

  • Bioinformatics Analysis

Input Requirements

  • ≥ 200 ng of purified genomic DNA

  • A260/280 = 1.8-2.0

  • No degradation, No contamination

Data Deliverable

  • Draft genome map

  • Genome preliminarily assembly

  • Genome component analysis

  • Gene function annotation

Phylogenetic tree of life Bacteria, Archaea, and Eukaryotes with various clades.

Phylogenomics of 10,575 genomes reveals evolutionary proximity between domains Bacteria and Archaea. Nat Commun 2019, 10(1):5477.

Collaborate with us

AGTC Genomics collaborates with researchers to apply genomics, multi-omics, and data-driven insights across discovery, translation, and development—accelerating innovation and real-world health impact.

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