Research Services
DNA Methylation Microarray
Applications
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Understanding the functional mechanisms at work in complex disease.
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Detecting altered methylation patterns and epigenetic changes that provide insight into tumorigenic pathways and cancer progression.
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Investigating the host methylation to infectious diseases.
DNA Methylation Analysis for Epigenome-Wide Association Studies
DNA methylation at the C5 position of cytosine plays a crucial role in gene expression and chromatin remodeling. Perturbations in methylation patterns are associated with tumorigenesis, neurodegenerative diseases and neurological disorders. Bioinformatic analysis of methylomes is widely used in various research areas, including studies on gene regulation, cell differentiation, embryogenesis, aging, occurrence and development of disease, phenotypic diversity and evolution in plants and animals.
What's Included
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Sample Receipt and Initial QC
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Library Construction and QC
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Sequencing and Data Delivery
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Bioinformatics Analysis
Input Requirements
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200-250ng of DNA (20ng/µL)
Data Deliverable
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Identifying differentially methylated CpGs
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Clustering Analysis
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Functional analysis
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GeneSet Enrichment Analysis
Whole blood DNA methylation analysis reveals respiratory environmental traits involved in COVID-19 severity following SARS-CoV-2 infection. Nat Commun 2022, 13(1):4597.
Collaborate with us
We act as scientific partners to help integrate human genetics into drug discovery and development. Whether identifying new targets, evaluating clinical-stage assets, or refining development strategies, Genomics delivers customised, data-driven approaches tailored to your strategic goals. Together we can accelerate drug discovery and advance population health to help people live longer, healthier lives.